LEI 11788 DE 08 PDF DOWNLOAD
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The serious pandemic threat associated with these events intensified the urgency of global pandemic preparedness for influenza H5N1 6.
In Maylei 11788 de 08 outbreak of influenza H5N1 in migratory waterfowl was observed at Qinghai Lake in western China 78. Possible spread to Europe by overlapping flyways was a concern 7.
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The first influenza H5N1 epizootics in the Russian Federation occurred at the end of July in the Novosibirsk region western Siberia 10 — 12which borders Kazakhstan and is near Mongolia and northwest China.
The outbreaks occurred in backyard poultry lei 11788 de 08 and small farms near lei 11788 de 08 of water where wild birds presumably stop to feed during seasonal migration. Several studies have reported high sequence homology of all gene segments of influenza H5N1 lei 11788 de 08 in from wild birds grebe in Novosibirsk Region and mute swan in Astrakhan Region and from poultry; these studies also examined the relations of outbreaks in poultry to migrations of wild birds 12 — However, evidence that wild migratory birds played a role in the spread of influenza H5N1 was not conclusive.
After the first outbreaks, influenza H5N1 spread rapidly westward through Russia; several outbreaks in poultry were reported in western Siberia and south and central European regions of the Russian Federation in late and early Figure 1.
Most of the outbreaks were similar to those first reported in western Siberia Analysis of deduced amino acid sequences of the M2 and neuraminidase proteins showed that all isolates are potentially sensitive to currently available antiviral drugs. Pathogenicity testing showed that all studied viruses were highly pathogenic in chickens; for 3 isolates tested lei 11788 de 08 mice and 2 tested in ferrets, pathogenicity was heterogeneous.
Pathogenicity in mammalian models was generally correlated with Lys at residue of polymerase basic protein 2.
Influenza viruses, H5N1, Russia, poultry, pathogenicity, research Highly pathogenic avian influenza viruses of the H5N1 subtype are zoonotic agents that present a continuing threat to animal and human health. Beforeinfluenza H5N1 was endemic in poultry in southern China 12 and occasionally caused severe disease in humans lei 11788 de 08 — 4.
The situation changed in late —, when the expanded geographic range of subtype H5N1 resulted in unprecedented epizootics in poultry and new human cases in eastern and southeastern Asia 56.
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The serious pandemic threat associated with these events intensified the urgency of global pandemic preparedness for influenza H5N1 6. In Mayan outbreak of influenza H5N1 in migratory waterfowl was observed at Lei 11788 de 08 Lake in western China 78. Possible spread to Europe by overlapping flyways was a concern 7.